Network pharmacology and experimental validation to investigate the mechanism of action of Zhilong Huoxue Tongyu capsule in the prevention and treatment of diabetic cardiomyopathy
Our results collectively indicated that ZL can effectively ameliorate diabetes cardiomyopathy, possibly by modulating the P38MAPK signaling pathway.
Authors
- H H Chen
- Gang Luo (ORCID: https://orcid.org/0000-0002-0487-2311)
- Sijin Yang (ORCID: https://orcid.org/0000-0002-7145-1285)
- Ping Liu (ORCID: https://orcid.org/0000-0001-7085-2098)
- Dan Wu (ORCID: https://orcid.org/0000-0001-5911-5951)
- Mengnan Liu (ORCID: https://orcid.org/0000-0001-9991-642X)
- Shan Li (ORCID: https://orcid.org/0000-0003-0231-4268)
- Fang Yang (ORCID: https://orcid.org/0000-0001-5644-5859)
- Dong Li (ORCID: https://orcid.org/0009-0003-0320-9045)
Institutions
- Southwest Medical University (CN)
Publication Details
- Journal
- PLoS ONE
- Published
- 2025-05-15
- DOI
- https://doi.org/10.1371/journal.pone.0323745
- Citations
- 2
- Primary Topic
- Pharmacological Effects of Natural Compounds
- Type
- article
- Field-Weighted Citation Impact
- 3.11
Funders
- Department of Science and Technology of Sichuan Province
- Luzhou Science and Technology Bureau