Influence of Osteolytic Lesions on the Fracture Process of the Proximal Femora

Osteolytic lesions form when metastatic cancer spreads to bone and causes tissue to decay, increasing the risk of pathological fractures. This study aims to provide medical professionals with a guide for determining whether to operate on a femur with detected lesions. 3D-generated Finite Element Analyses were performed on femur models in Abaqus to mimic a stance position. The force required for fracture and stiffness of the bone were extracted from each trial. Exploring other lesion specifications, bone properties, and load application methods can form a more comprehensive method of predicting the mechanical behavior of the femur. This could be a significant tool to aid in making critical treatment decisions for efficient patient care.