Evaluating the initial and end‐of‐day wettability of contemporary daily disposable contact lenses using various <i>in vitro</i> methods

The sessile drop technique produced the most measurable differences in wettability between different lens types, whereas the captive bubble technique was not able to provide any measurable differences between lenses. NIKBUT measurements may provide a better measure of on-eye wettability, but variability in the results using the current eye model still needs to be addressed in future studies for improved repeatability. Although the contact lenses showed different contact angles and NIKBUT results, their in vitro wettability did not significantly change over the 16 hours of simulated wear in terms of the captive bubble or NIKBUT values.

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Publication Details

Journal
Optometry and Vision Science
Published
2025-05-15
DOI
https://doi.org/10.1097/opx.0000000000002260
Primary Topic
Ocular Surface and Contact Lens
Type
article
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article

Evaluating the initial and end‐of‐day wettability of contemporary daily disposable contact lenses using various in vitro methods

H. Walther, James Yuliang Wu, Ying Zheng, Xinfeng Shi et al.
Optometry and Vision Science
Ocular Surface and Contact Lens
article

Evaluating the initial and end‐of‐day wettability of contemporary daily disposable contact lenses using various in vitro methods

H. Walther, James Yuliang Wu, Ying Zheng, Xinfeng Shi, Lakshman N. Subbaraman, Alex Hui, Lyndon Jones, Brandon Ho, Chau‐Minh Phan
article en

Abstract

The sessile drop technique produced the most measurable differences in wettability between different lens types, whereas the captive bubble technique was not able to provide any measurable differences between lenses. NIKBUT measurements may provide a better measure of on-eye wettability, but variability in the results using the current eye model still needs to be addressed in future studies for improved repeatability. Although the contact lenses showed different contact angles and NIKBUT results, their in vitro wettability did not significantly change over the 16 hours of simulated wear in terms of the captive bubble or NIKBUT values.

Optometry and Vision ScienceVol. 102(6)
University of Waterloo (CA), Australian College of Optometry (AU), UNSW Sydney (AU), Alcon (United States) (US), Vision Cooperative Research Centre (AU)
Openalex Percentile: Top 85%
Ocular Surface and Contact Lens
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