Evaluation of Liposomal Bupivacaine Use in Elective Cerebral Aneurysm Surgery

Our data illustrate that LB does not seem to affect average pain score, total opioid use, opioid cost, or LOS but does seem to be associated with an overall increase in total cost of pain medication owing to the significant cost of LB. We suspect that although pain control is important in cranial surgery, the effect of LB is not substantial enough to affect overall pain control in these patients and is not a primary driver of hospitalization. However, further prospective, randomized studies would be helpful to evaluate the overall benefit of LB on cranial surgery outcomes.