Serum NR1 and NR2 concentrations in first-episode schizophrenia and clinical high-risk for psychosis

Serum NR1 and NR2 concentrations show potential for early identification of individuals with psychosis, but further validation is needed, and they are also correlated with cognition. Furthermore, serum NR2 concentration is more stable and serves as a promising objective biomarker for quantitative assessment.

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Publication Details

Journal
BMC Psychiatry
Published
2025-05-15
DOI
https://doi.org/10.1186/s12888-025-06950-w
Primary Topic
Electrolyte and hormonal disorders
Type
article
Field-Weighted Citation Impact
0.00

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article

Serum NR1 and NR2 concentrations in first-episode schizophrenia and clinical high-risk for psychosis

Wenpeng Hou, Weiwei Hou, Xuemin Shi, Feng Li et al.
BMC Psychiatry
Electrolyte and hormonal disorders
article

Serum NR1 and NR2 concentrations in first-episode schizophrenia and clinical high-risk for psychosis

Wenpeng Hou, Weiwei Hou, Xuemin Shi, Feng Li, Yujie Wen, Qijing Bo, Yongying Cheng, Yushen Ding, Laramore Ge, Zhen Mao, Lu Wang, Feifei Wang, Xueqi Wang, Fang Dong
article en

Abstract

Serum NR1 and NR2 concentrations show potential for early identification of individuals with psychosis, but further validation is needed, and they are also correlated with cognition. Furthermore, serum NR2 concentration is more stable and serves as a promising objective biomarker for quantitative assessment.

BMC PsychiatryVol. 25(1)
Capital Medical University (CN), Beijing Anding Hospital (CN), Beijing Haidian Hospital (CN)
National Natural Science Foundation of China, Beijing Municipal Health Commission, Beijing Municipal Administration of Hospitals Clinical Medicine Development of Special Funding Support
Good health and well-being
Openalex Percentile: Top 82%
Electrolyte and hormonal disorders
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