Highly Luminescent Lanthanide Metal–Organic Frameworks for Trace Detection of Norfloxacin

Highly sensitive and selective detection of trace norfloxacin (NOR) in aqueous media was rarely reported by MOFs. Herein, a specific 2D TbMOF (terbium metal-organic framework) with outstanding luminescent properties was synthesized through simple bottom-up solvent-thermal methods. It exhibited prominent selectivity and stability toward NOR in ethanol through luminescence quenching with a <i>K</i>_sv value of 4.8 × 10⁴ M^-1 and a limit of detection of 0.14 μM. In addition to the low detection limit and high selectivity, the TbMOF prepared in this work also has a fast response time of less than 10 s, making it superior to other MOF-based luminescent sensors, which indicated the excellent sensitivity of our materials toward NOR at very low concentrations.