Genome-wide enhancer-gene regulatory maps of liver reveal novel regulatory mechanisms underlying NAFLD pathogenesis
Our study provides the most comprehensive ABC regulatory maps of the liver to date. This resource offers a valuable reference for identifying regulatory variants and prioritizing susceptibility genes of liver diseases, such as NAFLD.
Authors
- Wenyu Song (ORCID: https://orcid.org/0000-0002-1109-3148)
- Kaiyan Su
- Minggen Hu (ORCID: https://orcid.org/0000-0001-7933-7850)
- Tao Zeng (ORCID: https://orcid.org/0000-0003-3981-6675)
- Dandan Sun (ORCID: https://orcid.org/0000-0001-8548-1525)
- Liqun Xu (ORCID: https://orcid.org/0000-0002-6780-114X)
- Jinzhang Chen (ORCID: https://orcid.org/0000-0003-4964-2218)
- Haibei Xin (ORCID: https://orcid.org/0000-0002-8476-5451)
- Tianzhun Wu (ORCID: https://orcid.org/0000-0001-6237-169X)
- Yuanfeng Li (ORCID: https://orcid.org/0000-0001-8227-7019)
- Ruofan Li (ORCID: https://orcid.org/0009-0009-2391-8889)
- Mengya Zang
Institutions
- Harbin Medical University (CN)
- Guangxi Medical University (CN)
- China-Japan Friendship Hospital (CN)
- Chinese PLA General Hospital (CN)
- Third Affiliated Hospital of Harbin Medical University (CN)
- Beijing Proteome Research Center (CN)
- Chinese People's Liberation Army (CN)
- Southern Medical University (CN)
Publication Details
- Journal
- BMC Genomics
- Published
- 2025-05-15
- DOI
- https://doi.org/10.1186/s12864-025-11668-w
- Citations
- 2
- Primary Topic
- Liver Disease Diagnosis and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 2.71