Novel Synergized Aryl Amide Spatial Repellent Significantly Reduces Collections of Aedes Albopictus in a Wooded North Florida Suburban Residential Yard

Aedes albopictus is a significant vector of dengue and chikungunya to humans. Increasing evidence of resistance of this species coupled with their use of cryptic habitat pose significant obstacles to effective control. We investigated efficacy against natural populations of Ae. albopictus of a novel aryl amide spatial repellent (Compound 53) and a novel synergist (trans-chrysanthemic acid; TCA) that in previous work had shown high capability to repel Ae. aegypti in a laboratory environment. We observed a significant reduction in collections of Ae. albopictus in a wooded north Florida residential yard when synergized Compound 53/TCA was present. We conclude that this novel synergized aryl amide demonstrates potential and should be investigated further.