Sleep architecture characteristics in patients with acute ischemic stroke

To investigate the changes in sleep architecture in patients with acute ischemic stroke (AIS) accompanied by sleep-disordered breathing (SDB), providing a basis for clinical treatment strategies. 1367 patients with acute ischemic stroke within 48 h of onset who were hospitalized in the Department of Neurology of Kailuan General Hospital from November 2020 to December 2022 were selected. Among them, 963 cases were male and 404 cases were female, age: 33-92 (66.12 ± 10.62) years old.From the start of hospitalization, patients were monitored for 5 consecutive days using the intelligent mattress type sleep monitoring platform system (IMTSMPS). From day 1 to day 5, there was a difference in non-rapid eye movement 3 (NREM3) sleep (min) day two, and day five compared to day one in the ACI without SDB group (p = 0.019), and rapid eye movement (REM) sleep (min) day three compared to day five in the ACI with SDB group (p = 0.001). TST (min), SL (min), WASO (min), TOB (min), NOA (min), HRV1, fluctuated between 5 d in mild SDB group (p < 0.05). SL (min), TOB (min), NOA (min), and HAV1(%) in the moderate SDB group, with fluctuations between 5 d (P < 0.05). TST (min), SL (min), REML(min), NREM3 (min), REM (min), proportion of REM sleep(%), TOB (min), NOA (min)in severe SDB group, there were fluctuations between 5 d (P < 0.05). SDB is one of the most common concomitant symptoms in AIS patients and is closely associated with multiple forms of altered sleep structure. AIS patients without SDB mainly showed changes in NREM3 sleep structure. AIS and SDB patients mainly showed changes in the structure of REM sleep. Different levels of SDB in AIS patients lead to different forms of structural changes in sleep.