Evaluation of the effect of neoadjuvant chemotherapy on the planned resectability of extremity soft-tissue sarcomas
Despite tumour growth being observed in 75% of cases, the surgical resection strategy devised after neoadjuvant chemotherapy remained notably similar to the one devised prior to neoadjuvant chemotherapy for critical anatomical structures. However, 'switchers', namely patients identified as being at risk of needing an amputation if the tumour experiences slight growth, should undergo conservative surgery initially, followed by chemotherapy.
Authors
- Simon Tournemine
- Sylvie Bonvalot (ORCID: https://orcid.org/0000-0001-9726-9732)
- Dimosthenis Andreou (ORCID: https://orcid.org/0000-0002-5083-9678)
- David Biau (ORCID: https://orcid.org/0000-0001-5953-462X)
- Jean-Yves Mary
Institutions
- Inserm (FR)
- Université Paris Cité (FR)
- Hôpital Cochin (FR)
- Assistance Publique – Hôpitaux de Paris (FR)
- Essen University Hospital (DE)
- Hôpital Saint-Louis (FR)
- Institut Curie (FR)
Publication Details
- Journal
- Bone & Joint Open
- Published
- 2025-05-16
- DOI
- https://doi.org/10.1302/2633-1462.65.bjo-2025-0026.r1
- Primary Topic
- Sarcoma Diagnosis and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 0.00