Considerations on neurological deficits in patients with glioblastoma: impact of perilesional resection on neuro-oncological outcome. A monocentric real-life experience

Hemianopia has no impact on the patient's prognosis, while hemiparesis and aphasia at discharge worsen both PFS and OS prolonging time-to-treatment. When resecting GB, it is mandatory to avoid major neurological deficits that concur which reduce OS and PFS.

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Publication Details

Journal
Brain and Spine
Published
2025-01-01
DOI
https://doi.org/10.1016/j.bas.2025.104276
Citations
1
Primary Topic
Glioma Diagnosis and Treatment
Type
article
Field-Weighted Citation Impact
1.63
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Considerations on neurological deficits in patients with glioblastoma: impact of perilesional resection on neuro-oncological outcome. A monocentric real-life experience

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article

Considerations on neurological deficits in patients with glioblastoma: impact of perilesional resection on neuro-oncological outcome. A monocentric real-life experience

Andrea Trezza, Chiara Benedetta Rui, Giorgio Carrabba, Francesca Graziano, Andrea Di Cristofori, Davide Ferlito, Paola Rebora, Giovanni Palumbo, Chiara Julita, Gaia Chiarello, Fulvio Da Re, Maria Grazia Valsecchi, Carlo Giussani, G Stefanoni, Gianpaolo Basso
article en
1 citations

Abstract

Hemianopia has no impact on the patient's prognosis, while hemiparesis and aphasia at discharge worsen both PFS and OS prolonging time-to-treatment. When resecting GB, it is mandatory to avoid major neurological deficits that concur which reduce OS and PFS.

Brain and SpineVol. 5
Azienda Ospedaliera San Gerardo (IT), Istituti di Ricovero e Cura a Carattere Scientifico (IT), University of Milano-Bicocca (IT)
Zero hunger
Openalex Percentile: Top 17%
Glioma Diagnosis and Treatment
1.63
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