Relationship between renal function and cognitive impairment in patients with stable schizophrenia: a multicenter cross-sectional study
In hospitalized patients with stable schizophrenia, serum CysC levels are positively correlated with the severity of cognitive impairment, particularly showing significant associations with information processing speed and executive function. CysC may be a risk factor for exacerbating cognitive impairment in these patients. The combined diagnostic value of serum CysC, β2-MG, and UA demonstrated moderate accuracy in identifying stable schizophrenia cognitive impairment. These data support the potential of CysC as a biomarker of cognitive function in stable schizophrenia.
Authors
- Chengbing Huang
- Fenglan Wang (ORCID: https://orcid.org/0000-0003-1294-9320)
- Zhenlin Chen (ORCID: https://orcid.org/0000-0003-2100-1363)
- Cong Cao (ORCID: https://orcid.org/0000-0003-0824-3472)
- Wei-Shan Sun
- Aihua Zhou
- Tao Gu
- Xiyan Bao (ORCID: https://orcid.org/0000-0001-6862-2672)
- Xuebin Qu
- Lingling Hua (ORCID: https://orcid.org/0000-0002-6885-3005)
- Sumei Shen
- Xuehao Xu
Institutions
- Nanjing Brain Hospital (CN)
- Nanjing Medical University (CN)
Publication Details
- Journal
- BMC Psychiatry
- Published
- 2025-05-15
- DOI
- https://doi.org/10.1186/s12888-025-06952-8
- Citations
- 2
- Primary Topic
- Schizophrenia research and treatment
- Type
- article
- Field-Weighted Citation Impact
- 2.94
Funders
- Government of Jiangsu Province