Scaling of vagus nerve stimulation parameters does not achieve equivalent nerve responses across species
The results highlight the need for systematic approaches to select stimulation parameters that account for individual- and species-specific differences in nerve responses to stimulation. Such parameter tuning may lead to higher response rates and greater therapeutic benefits from VNS therapies.
Authors
- Nicole A. Pelot (ORCID: https://orcid.org/0000-0003-2844-0190)
- Warren M. Grill (ORCID: https://orcid.org/0000-0001-5240-6588)
- Eric D Musselman (ORCID: https://orcid.org/0000-0001-5295-7267)
- Ishani Raha (ORCID: https://orcid.org/0000-0002-2180-5268)
Institutions
- Duke University (US)
- Duke University Hospital (US)
Publication Details
- Journal
- Bioelectronic Medicine
- Published
- 2025-05-15
- DOI
- https://doi.org/10.1186/s42234-025-00174-9
- Citations
- 5
- Primary Topic
- Vagus Nerve Stimulation Research
- Type
- article
- Field-Weighted Citation Impact
- 4.21
Funders
- Scheme for Promotion of Academic and Research Collaboration
- National Institutes of Health