Protective effect of menthol against diethylnitrosamine-induced hepatocellular carcinoma in mice by downregulating <i>CTNNB1</i> and <i>HIF-1α</i>.
We concluded that menthol inhibits Wnt signaling and suppresses the expression of <i>HIF-1α</i> and <i>VEGF</i> in the liver of DEN-injected mice. It is probably a suitable option for the prevention and treatment of hepatocellular carcinoma.
Authors
- Masoumeh Asle‐Rousta (ORCID: https://orcid.org/0000-0002-2087-5483)
- Golnaz Asaadi Tehrani (ORCID: https://orcid.org/0000-0002-3987-5766)
- Zahra Mollaei
Institutions
- Islamic Azad University of Zanjan (IR)
Publication Details
- Journal
- PubMed
- Published
- 2025-01-01
- DOI
- https://doi.org/10.22038/ajp.2024.25230
- Primary Topic
- Ginger and Zingiberaceae research
- Type
- article
- Field-Weighted Citation Impact
- 0.00