Neuroprotective effects of hesperidin and auraptene on 6-hydroxydopamine-induced neurodegeneration in SH-SY5Y cells.
HES protects SH-SY5Y cells against 6-OHDA-induced neural damage via inhibiting G2/M arrest, reducing the amount of ROS, and increasing cell viability. However, the different effects and more precise mechanisms are still unknown, and requires new research on animal and human models.
Authors
- Elaheh Gheybi
- Mehdi Rostami (ORCID: https://orcid.org/0000-0002-7228-1273)
- Seyed Hadi Mousavi (ORCID: https://orcid.org/0000-0002-4686-5232)
- Mohammad Soukhtanloo
- Roghayeh Rashidi
- Seyed Isaac Hashemy
- Malihe Mehrparvar Tajoddini
Institutions
- Mashhad University of Medical Sciences (IR)
Publication Details
- Journal
- PubMed
- Published
- 2025-01-01
- DOI
- https://doi.org/10.22038/ajp.2024.25214
- Citations
- 1
- Primary Topic
- Plant chemical constituents analysis
- Type
- article
- Field-Weighted Citation Impact
- 1.75
Funders
- Mashhad University of Medical Sciences