[A Case of Advanced Gastric Cancer with Cervical Lymph Node Metastasis Responding to SOX+Nivolumab and Treated with Conversion Surgery].

A66-year-old man was diagnosed with gastric cancer with cervical lymph node metastasis(cT4aN1pM1, Stage ⅣB). He received chemotherapy with 4 courses of SOX+nivolumab. The primary gastric tumor had shrunk significantly and the cervical lymph nodes could no longer be identified. The therapeutic effect was judged as partial response(PR). We decided to performed conversion surgery. Total gastrectomy and left cervical lymphadenectomy were performed. Histological examination revealed a Grade 2a response in the primary tumor, with no viable tumor cells found in the cervical lymph nodes (ypT4aN1M0, Stage ⅢA). Postoperative adjuvant chemotherapy with nivolumab was initiated. Approximately 16 months after surgery, no apparent recurrence has been observed.

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Journal
PubMed
Published
2025-04-01
Primary Topic
Gastric Cancer Management and Outcomes
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article
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article

[A Case of Advanced Gastric Cancer with Cervical Lymph Node Metastasis Responding to SOX+Nivolumab and Treated with Conversion Surgery].

Daisuke Takiuchi, Yusuke Akamaru, Takuya Hamakawa, Kohji Nishida et al.
PubMed
Gastric Cancer Management and Outcomes
article

[A Case of Advanced Gastric Cancer with Cervical Lymph Node Metastasis Responding to SOX+Nivolumab and Treated with Conversion Surgery].

Daisuke Takiuchi, Yusuke Akamaru, Takuya Hamakawa, Kohji Nishida, Masatoshi Nomura, Hiromichi Miyagaki, Koki Tamai, Mitsuyoshi Tei, Masanori Tsujie, Kazuhiro Ishimaru, Soichiro Mori, Yukihiro Yoshikawa
article en

Abstract

A66-year-old man was diagnosed with gastric cancer with cervical lymph node metastasis(cT4aN1pM1, Stage ⅣB). He received chemotherapy with 4 courses of SOX+nivolumab. The primary gastric tumor had shrunk significantly and the cervical lymph nodes could no longer be identified. The therapeutic effect was judged as partial response(PR). We decided to performed conversion surgery. Total gastrectomy and left cervical lymphadenectomy were performed. Histological examination revealed a Grade 2a response in the primary tumor, with no viable tumor cells found in the cervical lymph nodes (ypT4aN1M0, Stage ⅢA). Postoperative adjuvant chemotherapy with nivolumab was initiated. Approximately 16 months after surgery, no apparent recurrence has been observed.

PubMedVol. 52(4)
Osaka Rosai Hospital (JP)
Openalex Percentile: Top 83%
Gastric Cancer Management and Outcomes
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