Non-functioning pancreatic neuroendocrine tumor presenting with acute pancreatitis: a case report

Pancreatic neuroendocrine tumors (pNETs) are a group of tumors with complex therapeutic options that differ according to pathological grading, clinical staging, and the existence of hormone secretion symptoms. We report a 34-year-old male with recurrent acute pancreatitis due to a non-functioning pNET. He presented with intermittent epigastric pain and elevated pancreatic enzymes. MRCP and endoscopic ultrasound revealed an oval lesion near the pancreatic head, confirmed as a grade 1 neuroendocrine tumor on biopsy. A Whipple procedure was performed based on tumor size and location. This case highlights the rare occurrence of pNET presenting with acute pancreatitis.