Predictors of in-hospital mortality in adult sepsis patients admitted to intensive care unit

Sepsis is a critical condition associated with high morbidity and mortality in hospitalized patients. This study aims to identify predictors of in-hospital mortality among adult sepsis patients admitted to the Intensive Care Unit (ICU), with the goal of improving clinical outcomes and optimizing resource allocation. An observational study was conducted over one year in a surgical ICU, involving 160 adult patients diagnosed with sepsis and septic shock. Data collected included demographics, comorbidities, Sequential Organ Failure Assessment (SOFA) scores, and laboratory results. The mortality rate was analyzed in relation to these factors. The study found a mortality rate of 35.67%, with a higher incidence in females. The mean APACHE IV score for survivors was 46.84, while non-survivors had a mean score of 69.35. Initial SOFA scores were significantly higher in non-survivors, indicating a correlation between organ dysfunction and mortality. These findings highlight the importance of early identification and management of sepsis to improve patient outcomes.