Leveraging positive interactions in nature to enhance the shared goals and success of One Health

Abstract Cooperative and positive interactions are ubiquitous across all levels of biological organization, and these play critically important roles in the ecology and evolution of natural systems. Among these are long-established interactions between humans and nature to the benefit of both. The development and persistence of these relationships in nature entail processes—mobilization, incentivization, accountability—that can inform approaches for building collaborations across One Health initiatives. Protecting and leveraging these cooperative and positive interactions can facilitate One Health in achieving its goals of optimizing the health of people, animals, and ecosystems. Positive human interventions in the Anthropocene require both human cooperation and learning from lessons from biology to be embraced in how humans interact with nature and one another.