Comprehensive analysis of mRNA and lncRNA expression for predicting lymph node metastasis in cervical cancer: a novel seven-gene signature approach
We constructed a reliable prediction model of LNM in CC patients with a seven-mRNA-lncRNA gene cluster. This model guides lymphadenectomy decisions, reduces overtreatment, and enhances patient survival. Our work bridges molecular insights with clinical practice and provides a foundation for further research into the management of CC.
Authors
- Yumei Wu (ORCID: https://orcid.org/0000-0002-4828-8408)
- Ming Wang (ORCID: https://orcid.org/0000-0002-1959-4879)
- Jiahui Wei (ORCID: https://orcid.org/0000-0002-4446-8460)
Institutions
- Beijing Obstetrics and Gynecology Hospital (CN)
Publication Details
- Journal
- Frontiers in Genetics
- Published
- 2025-05-15
- DOI
- https://doi.org/10.3389/fgene.2025.1524821
- Primary Topic
- Cancer-related molecular mechanisms research
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Beijing Municipal Science and Technology Commission