Study on the mechanism by which Xuanfu Hua Tang increases sensitivity of hepatocellular carcinoma cells to sorafenib by antagonizing the Notch1 pathway through HIF-2α
Xuanfu HT can increase sorafenib sensitivity of hepatocellular carcinoma cells by antagonizing the Notch1 pathway through quercetin-binding HIF-2α.
Authors
- Yi-Wan Shang
- Wen-Zhao Luo
- Zhen Chen (ORCID: https://orcid.org/0000-0002-6289-4332)
- Yinglin Cui (ORCID: https://orcid.org/0000-0001-8703-6257)
- Xian Li (ORCID: https://orcid.org/0000-0001-7660-5290)
Institutions
- Henan University of Traditional Chinese Medicine (CN)
- Zhengzhou City Hospital (CN)
- First Affiliated Hospital of Henan University (CN)
Publication Details
- Journal
- Frontiers in Oncology
- Published
- 2025-05-15
- DOI
- https://doi.org/10.3389/fonc.2025.1552480
- Primary Topic
- Cancer-related molecular mechanisms research
- Type
- article
- Field-Weighted Citation Impact
- 0.00