Impact of the Triglyceride–Glucose index on all-cause and cardiovascular mortalities across different metabolic health and obesity statuses in US adults

The TyG index is positively correlated with mortality risk in the overall and metabolically unhealthy populations but not in the metabolically healthy populations. This finding indicates that the predictive value of the TyG index for mortality differs across populations, highlighting the necessity of accounting for metabolic status when the TyG index is used for prognostic evaluation.