ADSC-derived exosomes mitigate radiation-induced skin injury by reducing oxidative stress, inflammation and cell death
ADSC-Exo alleviated RISI through multifaceted effects, including macrophage polarization modulation, inflammation suppression, oxidative stress reduction, and inhibition of apoptosis and pyroptosis. These findings support the potential of ADSC-Exo as a promising cell-free therapy for RISI.
Authors
- Yakun Gao (ORCID: https://orcid.org/0000-0001-6304-1254)
- Hao Hu (ORCID: https://orcid.org/0000-0002-1127-0589)
- Hua Jiang
- Jiawei Gu
- Zhe Liu (ORCID: https://orcid.org/0009-0004-1429-9207)
Institutions
- Fudan University (CN)
- Shanghai East Hospital (CN)
- Huashan Hospital (CN)
Publication Details
- Journal
- Frontiers in Public Health
- Published
- 2025-05-14
- DOI
- https://doi.org/10.3389/fpubh.2025.1603431
- Citations
- 3
- Primary Topic
- Extracellular vesicles in disease
- Type
- article
- Field-Weighted Citation Impact
- 2.42
Funders
- Tongji University