Koopman-based linearization of preparatory EEG dynamics in Parkinson’s disease during galvanic vestibular stimulation
GVS enhances motor preparation in PD by restoring healthy cortical EEG patterns, with additive benefits from dopaminergic medication. The Deep Koopman framework offers a powerful approach for dissecting complex EEG dynamics and designing targeted neuromodulation strategies. These findings elucidate GVS's therapeutic mechanisms and highlight its potential for personalized PD interventions, warranting further exploration in larger cohorts and varied stimulation protocols.
Authors
- Martin J. McKeown (ORCID: https://orcid.org/0000-0002-4048-0817)
- Maryam S. Mirian (ORCID: https://orcid.org/0000-0001-5411-9902)
- Emad Arasteh (ORCID: https://orcid.org/0009-0001-8072-9322)
- Artur Luczak (ORCID: https://orcid.org/0000-0002-4929-5781)
- Abhijit Chinchani (ORCID: https://orcid.org/0000-0001-5950-4332)
- Mahbobeh Faramarzi (ORCID: https://orcid.org/0000-0002-3568-7039)
- Maryam Kia (ORCID: https://orcid.org/0000-0002-1346-8820)
- Soojin Lee (ORCID: https://orcid.org/0000-0002-6258-1280)
- Saeed Soori
- Saeed Saedi
Institutions
- University of Lethbridge (CA)
- Sharif University of Technology (IR)
- University of British Columbia (CA)
- University of Toronto (CA)
- University of Tehran (IR)
- University Medical Center Utrecht (NL)
- Wilhelmina Children's Hospital (NL)
Publication Details
- Journal
- Frontiers in Human Neuroscience
- Published
- 2025-05-14
- DOI
- https://doi.org/10.3389/fnhum.2025.1566566
- Primary Topic
- Muscle activation and electromyography studies
- Type
- article
- Field-Weighted Citation Impact
- 0.00