Type III interferon, age and IFNL gene single nucleotide polymorphisms determine the characteristics of H1N1 influenza infection
This is the first study to comprehensively explore the impact of host factors, especially IFN-λ polymorphisms, on H1N1 virus infection. Further elucidation of the underlying mechanisms may help to develop novel prevention and treatment strategies for influenza virus infection.
Authors
- Wenbo Zhu (ORCID: https://orcid.org/0000-0002-2637-564X)
- Hongbo Zhang (ORCID: https://orcid.org/0000-0003-3316-9403)
- Shao Wang
- Shuangquan Liu (ORCID: https://orcid.org/0000-0002-2690-2665)
- Chenchen Guan (ORCID: https://orcid.org/0009-0009-3311-4243)
Institutions
- University of Pittsburgh (US)
- Animal Science Research Institute (CN)
- Fujian Academy of Agricultural Sciences (CN)
- First Affiliated Hospital of University of South China (CN)
- University of South China (CN)
Publication Details
- Journal
- Frontiers in Immunology
- Published
- 2025-05-14
- DOI
- https://doi.org/10.3389/fimmu.2025.1592841
- Citations
- 4
- Primary Topic
- Influenza Virus Research Studies
- Type
- article
- Field-Weighted Citation Impact
- 5.42