Integrating network pharmacology, quantitative transcriptomic analysis, and experimental validation revealed the mechanism of cordycepin in the treatment of obesity
This study comprehensively uncovers the potential mechanism of Cpn against obesity based on network pharmacology and quantitative transcriptomics, which provides evidence for revealing the pathogenesis of obesity, suggesting that Cpn is a possible lead compound for anti-obesity treatment.
Authors
- Yu‐Mei Liao (ORCID: https://orcid.org/0000-0001-9916-9356)
- Fuli Qin
- Mingchao Wang (ORCID: https://orcid.org/0000-0002-1894-3758)
- Can Liu (ORCID: https://orcid.org/0009-0006-8694-9322)
- Jiemei Chen (ORCID: https://orcid.org/0000-0001-9989-462X)
Institutions
- Guangxi Medical University (CN)
- Chinese Academy of Medical Sciences & Peking Union Medical College (CN)
- First Affiliated Hospital of GuangXi Medical University (CN)
Publication Details
- Journal
- Frontiers in Pharmacology
- Published
- 2025-05-14
- DOI
- https://doi.org/10.3389/fphar.2025.1571480
- Citations
- 5
- Primary Topic
- Metabolism, Diabetes, and Cancer
- Type
- article
- Field-Weighted Citation Impact
- 4.03
Funders
- Natural Science Foundation of Guangxi Province
- Guangxi Medical University