A single-institution experience with intraoperative in vivo confocal laser endomicroscopy for brain tumors in 50 patients
The clinically approved CLE system allows intraoperative <i>in vivo</i> visualization of tissue histoarchitecture and identification of lesional tissue in real time, without the need for tissue biopsy and processing. CLE is efficient and cost-effective, with high diagnostic accuracy at the glioma core. However, CLE imaging at the tumor margin remains challenging.
Authors
- Irakliy Abramov (ORCID: https://orcid.org/0000-0003-4644-8727)
- Kris A. Smith (ORCID: https://orcid.org/0000-0003-4645-6313)
- Kıvanç Yangı (ORCID: https://orcid.org/0000-0003-0500-218X)
- Yuan Xu (ORCID: https://orcid.org/0000-0003-1959-9861)
- Oscar Alcantar-Garibay
- Joelle N. Hartke
- Randall W. Porter
- Michael T. Lawton (ORCID: https://orcid.org/0000-0002-8020-6388)
- Thomas J. On (ORCID: https://orcid.org/0009-0005-7449-4204)
- Mark C. Preul (ORCID: https://orcid.org/0000-0001-8970-161X)
- Jennifer M. Eschbacher
Institutions
- Barrow Neurological Institute (US)
- St. Joseph's Hospital and Medical Center (US)
Publication Details
- Journal
- Frontiers in Oncology
- Published
- 2025-05-14
- DOI
- https://doi.org/10.3389/fonc.2025.1565935
- Citations
- 2
- Primary Topic
- MRI in cancer diagnosis
- Type
- article
- Field-Weighted Citation Impact
- 2.72
Funders
- Barrow Neurological Foundation