Individual alpha frequency tACS reduces static functional connectivity across the default mode network
Against our initial hypothesis, IAF-tACS reduced sFC in the DMN, possibly due to phase disparities introduced by cortical gyrification. These findings suggest that tACS might modulate FC in a more complex manner than previously thought, highlighting the need for further research into the personalized application of neuromodulation techniques, as well as its potential therapeutic implications for conditions like Alzheimer's disease.
Authors
- Jesús Cabrera-Álvarez (ORCID: https://orcid.org/0000-0003-2384-7231)
- Fernando Maestú (ORCID: https://orcid.org/0000-0002-3195-0071)
- A. Santos (ORCID: https://orcid.org/0000-0001-7423-9135)
- Carlos J. Gómez‐Ariza (ORCID: https://orcid.org/0000-0001-5889-7533)
- Alejandra García‐Colomo (ORCID: https://orcid.org/0000-0003-1817-6007)
- Alberto del Cerro‐León (ORCID: https://orcid.org/0000-0003-0630-0373)
- Martín Carrasco-Gómez (ORCID: https://orcid.org/0000-0003-4735-4562)
Institutions
- Universidad Complutense de Madrid (ES)
- Universidad de Jaén (ES)
- Instituto de Salud Carlos III (ES)
- Instituto de Investigación Sanitaria del Hospital Clínico San Carlos (ES)
- Biomedical Research Networking Center in Bioengineering, Biomaterials and Nanomedicine (ES)
- Universidad Politécnica de Madrid (ES)
Publication Details
- Journal
- Frontiers in Human Neuroscience
- Published
- 2025-05-14
- DOI
- https://doi.org/10.3389/fnhum.2025.1534321
- Citations
- 2
- Primary Topic
- Functional Brain Connectivity Studies
- Type
- article
- Field-Weighted Citation Impact
- 2.86