Osteoarthritis Inflammation and Proprioceptive Interactions and Targets

Joints are sensitive structures whose qualitative and quantitative components depend not only on the harmonious interactions of hormones, enzymes, vitamins, minerals and protein, but also on the stresses put upon them by function as well as their intrinsic and extrinsic neuromotor environments, activity, and integrity. This paper reviews some recent pathological insights regarding the synovial membrane and its cells that indicate when injured may evoke a possible inflammatory pathway of inevitable joint destruction unless abated. One essential movement correlate that may fail to limit the spread of osteoarthritis severity, namely proprioception is specifically explored. Based on what is known we argue in favor of its possible untapped utility in efforts to reverse or mitigate the onset of post traumatic arthritis, especially in the face of persistent inflammation.