Advances in the Application of Magnetic Resonance Elastography in Liver Fibrosis: Technological Innovation and Clinical Practice

磁共振弹性成像(magnetic resonance elastography, MRE)作为一种非侵入性的医学影像技术，近年来在肝纤维化的检测中展现了重要的应用价值。与传统活检方法相比，MRE不仅避免了取样误差和潜在并发症的风险，而且能够提供整个肝脏的全面信息，实现了从局部到整体的诊断转变。在临床实践中，MRE已被广泛应用于监测肝纤维化患者的病情进展、指导个性化治疗方案的选择，并在预测肝硬化及其并发症方面显示出巨大潜力。本文综述了MRE在肝纤维化中的应用进展，包括其技术原理、临床应用、局限及未来发展方向，特别关注其在肝纤维化监测中的创新应用。通过结合最新的研究成果和临床实践，本文旨在为临床医生和研究人员提供一个全面的视角，以更好地理解和应用这一技术。Magnetic resonance elastography (MRE), as a non-invasive medical imaging technique, has demonstrated profound application value in the detection of liver fibrosis in recent years. Compared to traditional biopsy methods, MRE not only avoids the risks of sampling errors and potential complications but also provides comprehensive information about the entire liver, achieving a diagnostic shift from local to global assessment. In clinical practice, MRE has been widely used to monitor the progression of liver fibrosis patients, guide the selection of personalized treatment plans, and has shown great potential in predicting liver cirrhosis and its complications. This article reviews the progress of MRE application in liver fibrosis, including its technical principles, clinical applications, limitations, and future development directions, with particular focus on its innovative application in liver fibrosis monitoring. By combining the latest research findings and clinical practices, this article aims to provide clinicians and researchers with a comprehensive perspective to better understand and apply this technology.