Rapid severe hypertension and organ damage in two‐kidney two‐clip rats produced by different sizes of clips
2K2C can produce severe hypertension and multi-organ damage in a short time. 2K2C rats in 0.2 mm clips can be used as a hypertensive emergency model. This study provides crucial insights for guiding the development of targeted interventions.
Authors
- Qi‐Sheng Ling
- Daoxin Wang (ORCID: https://orcid.org/0000-0001-8327-3650)
- Chao‐Yu Miao (ORCID: https://orcid.org/0000-0002-8176-3434)
- Yu‐Chen Wei (ORCID: https://orcid.org/0000-0003-2460-0492)
- Jia‐Sheng Tian
Institutions
- Shanghai University (CN)
- Second Military Medical University (CN)
Publication Details
- Journal
- Animal Models and Experimental Medicine
- Published
- 2025-05-14
- DOI
- https://doi.org/10.1002/ame2.70027
- Citations
- 2
- Primary Topic
- Renal and Vascular Pathologies
- Type
- article
- Field-Weighted Citation Impact
- 3.04
Funders
- National Natural Science Foundation of China