Comprehensive network pharmacology and experimentation to unveil the therapeutic efficacy and mechanisms of gypenoside LI in anaplastic thyroid cancer
Gyp LI effectively inhibits ATC progression by modulating SRC/PI3K/AKT signaling, enhancing apoptosis, and promoting iodine uptake, offering potential therapeutic benefits for ATC treatment.
Authors
- Qin Peng (ORCID: https://orcid.org/0000-0001-6243-3416)
- Zanbing Li
- Xiangtai Zeng (ORCID: https://orcid.org/0000-0002-4788-1533)
- Weixiang Liu (ORCID: https://orcid.org/0000-0001-7198-6311)
- Hong Liao
- Yong Ying (ORCID: https://orcid.org/0000-0002-8365-4303)
- Jiafeng Liu (ORCID: https://orcid.org/0009-0005-5530-8744)
- Yang Xie (ORCID: https://orcid.org/0000-0003-1875-804X)
- M. Y. Liu
- Junwei Huang (ORCID: https://orcid.org/0000-0002-8182-9448)
- Min-chao Dai
Institutions
- Ganzhou People's Hospital (CN)
- Gannan Medical University (CN)
- First Affiliated Hospital of Gannan Medical University (CN)
Publication Details
- Journal
- BMC Cancer
- Published
- 2025-05-14
- DOI
- https://doi.org/10.1186/s12885-025-14231-8
- Citations
- 2
- Primary Topic
- Ginseng Biological Effects and Applications
- Type
- article
- Field-Weighted Citation Impact
- 1.61
Funders
- National Natural Science Foundation of China