Impact of Aspirin on Timing of Birth in Pregnancies With Clinical Manifestations of Placental Dysfunction: Evidence From a Multicentre Randomised Clinical Trial
In this secondary analysis of a cluster randomised trial, women at high risk of PE who are destined to develop a clinical spectrum of PD may benefit from longer pregnancy duration through aspirin administration in early pregnancy. Aspirin may delay the GAD due to PD, particularly benefiting those deliveries that would occur at earlier gestations without aspirin administration.
Authors
- Eve Tang
- Yun-ping Wu
- Liona C. Poon (ORCID: https://orcid.org/0000-0002-3944-4130)
- Mayumi Kaneko (ORCID: https://orcid.org/0000-0002-0613-446X)
- Long Nguyen‐Hoang
- Steven W. Shaw (ORCID: https://orcid.org/0000-0002-3931-7297)
- Mingming Zheng (ORCID: https://orcid.org/0000-0003-0611-5581)
- Angela Aguilar
- Tung‐Yao Chang (ORCID: https://orcid.org/0000-0001-8217-5530)
- Noppadol Chaiyasit (ORCID: https://orcid.org/0000-0002-6541-5990)
- Ka Chun Chong (ORCID: https://orcid.org/0000-0001-5610-1298)
- Ritsuko K. Pooh (ORCID: https://orcid.org/0000-0002-1527-4595)
- Daljit Singh Sahota (ORCID: https://orcid.org/0000-0002-3755-2701)
- Ioannis Papastefanou (ORCID: https://orcid.org/0000-0002-7969-1435)
- Yali Hu (ORCID: https://orcid.org/0000-0001-5475-7840)
- Raden Aditya Kusuma (ORCID: https://orcid.org/0000-0002-9164-4471)
- Tongta Nanthakomon
- Suchaya Luewan (ORCID: https://orcid.org/0000-0002-4838-175X)
- Arihiro Shiozaki (ORCID: https://orcid.org/0000-0002-8000-6116)
- Piengbulan Yapan
- Mahesh Choolani (ORCID: https://orcid.org/0000-0001-8336-0973)
- Wing Cheong Leung (ORCID: https://orcid.org/0000-0003-1851-2138)
- Diem Thi Nguyen (ORCID: https://orcid.org/0000-0002-9680-5772)
- Yun-Yu Chen (ORCID: https://orcid.org/0000-0002-5632-3445)
- Yanmin Jiang (ORCID: https://orcid.org/0000-0003-1437-6749)
- Nikki Lee (ORCID: https://orcid.org/0000-0003-4565-1280)
- Linh Thuy Dinh (ORCID: https://orcid.org/0009-0002-3456-7518)
- S. Lau
- Ainaa Syazana Mohamad
Institutions
- Thammasat University (TH)
- Siriraj Hospital (TH)
- National University of Singapore (SG)
- Chinese University of Hong Kong (HK)
- King's College London (GB)
- Kwong Wah Hospital (CN)
- Philippine General Hospital (PH)
- King Chulalongkorn Memorial Hospital (TH)
- Chang Gung Memorial Hospital (TW)
- Kunming Children's Hospital (CN)
- Hong Kong Jockey Club (HK)
- Nanjing Drum Tower Hospital (CN)
- Prince of Wales Hospital (CN)
- Osaka Nishi Clinic (JP)
- Pembuluh Darah Harapan Kita (ID)
- Khanh Hoa General Hospital (VN)
- National University Health System (SG)
- Viet Duc Hospital (VN)
- SHOWA Medical University Hospital (JP)
- University of Toyama (JP)
- Chiang Mai University (TH)
- National University of Malaysia (MY)
- Guangzhou Medical University (CN)
Publication Details
- Journal
- BJOG An International Journal of Obstetrics & Gynaecology
- Published
- 2025-05-14
- DOI
- https://doi.org/10.1111/1471-0528.18211
- Citations
- 4
- Primary Topic
- Pregnancy and preeclampsia studies
- Type
- article
- Field-Weighted Citation Impact
- 8.23
Funders
- Guangzhou Medical University
- Thermo Fisher Scientific
- National University of Singapore
- Jichi Medical University
- Chinese University of Hong Kong
- Kunming University of Science and Technology
- GE Healthcare
- Roche Diagnostics
- Faculty of Medicine Siriraj Hospital, Mahidol University