The green tea component (−)-epigallocatechin-3-gallate protects against cytokine-induced epithelial barrier damage in intestinal epithelial cells
The green tea component EGCG stabilizes the intestinal barrier and protects against barrier dysfunction induced by pro-inflammatory cytokines. These findings highlight the potential of EGCG as a supportive treatment strategy for IBD.
Authors
- Jörg–Dieter Schulzke (ORCID: https://orcid.org/0000-0001-9947-5521)
- Nina A. Hering (ORCID: https://orcid.org/0000-0001-9751-6967)
- Rita Rosenthal (ORCID: https://orcid.org/0000-0002-5807-9415)
- Kopano Valerie Masete
- Alain S. Massarani
- Anne Waesch
Institutions
- Charité - Universitätsmedizin Berlin (DE)
Publication Details
- Journal
- Frontiers in Pharmacology
- Published
- 2025-05-14
- DOI
- https://doi.org/10.3389/fphar.2025.1559812
- Citations
- 4
- Primary Topic
- Tea Polyphenols and Effects
- Type
- article
- Field-Weighted Citation Impact
- 5.89
Funders
- Deutsche Forschungsgemeinschaft