Trough value prediction using umbilical blood cystatin C value during tobramycin administration
Umbilical cord blood CysC/GW/BSA values were strongly correlated with TOB trough values. Cord blood samples can be used to estimate trough values before drug administration without increasing the risk to infants associated with invasive tests, enabling determination of the dosage that will not cause nephrotoxicity.
Authors
- Ayaka Fukui
- Takayuki Suzuki (ORCID: https://orcid.org/0000-0002-6532-9363)
- Kentaro Hirayama
- Takuya Sugimoto (ORCID: https://orcid.org/0000-0002-2048-5450)
- Mitsuhiko Riko
- Tomoya Tsuchihashi (ORCID: https://orcid.org/0000-0002-3042-4715)
- Daisuke Tokuhara (ORCID: https://orcid.org/0000-0002-2441-5062)
- Takeshi Kumagai (ORCID: https://orcid.org/0000-0001-6387-0554)
Institutions
- Wakayama Medical University (JP)
Publication Details
- Journal
- Pediatrics International
- Published
- 2025-01-01
- DOI
- https://doi.org/10.1111/ped.70041
- Primary Topic
- Neonatal Health and Biochemistry
- Type
- article
- Field-Weighted Citation Impact
- 0.00