WDR62 affects the progression of ovarian cancer by regulating the cell cycle
WDR62 is overexpressed in ovarian cancer and is closely related to the prognosis of ovarian cancer patients. WDR62 promotes ovarian cancer progression by regulating the cell cycle and may influence its development through interaction with MAPK8 to mediate the JNK signaling pathway. These findings suggest that WDR62 could be a potential target for the early screening, diagnosis, and treatment of ovarian cancer.
Authors
- Ying Shang (ORCID: https://orcid.org/0000-0002-1496-1799)
- Yuhang Zhang (ORCID: https://orcid.org/0000-0002-9738-5343)
- Ye Kuang
- Yuqi Yang (ORCID: https://orcid.org/0000-0003-2961-5677)
- Lingqi Zhang
- Wanting Jing
Institutions
- Harbin Medical University (CN)
Publication Details
- Journal
- Hereditas
- Published
- 2025-05-14
- DOI
- https://doi.org/10.1186/s41065-025-00444-1
- Citations
- 1
- Primary Topic
- RNA modifications and cancer
- Type
- article
- Field-Weighted Citation Impact
- 0.81
Funders
- Natural Science Foundation of Heilongjiang Province