Formulation and Optimization of Pyrazinamide-Loaded Solid Lipid Nanoparticles by Employing a Design of Experiments Approach

PYZ-SLNs could be a promising carrier for the treatment of TB via the oral intestinal lymphatic pathway, circumventing its hepatic first-pass metabolism and thereby preventing hepatic adverse effects.

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Publication Details

Journal
Turkish Journal of Pharmaceutical Sciences
Published
2025-05-14
DOI
https://doi.org/10.4274/tjps.galenos.2025.66350
Citations
4
Primary Topic
Computational Drug Discovery Methods
Type
article
Field-Weighted Citation Impact
6.02
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article

Formulation and Optimization of Pyrazinamide-Loaded Solid Lipid Nanoparticles by Employing a Design of Experiments Approach

Nimitt V. Chokshi, Preksha Vinchhi, M.D. Shrimali A.C. Patel
4 citations
Turkish Journal of Pharmaceutical Sciences
Computational Drug Discovery Methods
6.02
article

Formulation and Optimization of Pyrazinamide-Loaded Solid Lipid Nanoparticles by Employing a Design of Experiments Approach

Nimitt V. Chokshi, Preksha Vinchhi, M.D. Shrimali A.C. Patel
article en
4 citations

Abstract

PYZ-SLNs could be a promising carrier for the treatment of TB via the oral intestinal lymphatic pathway, circumventing its hepatic first-pass metabolism and thereby preventing hepatic adverse effects.

Turkish Journal of Pharmaceutical SciencesVol. 22(2)
Nirma University (IN)
Openalex Percentile: Top 4%
Computational Drug Discovery Methods
6.02
DOIOpen Access PDFOpenAlex
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Formulation and Optimization of Pyrazinamide-Loaded Solid Lipid Nanoparticles by Employing a Design of Experiments Approach — Nimitt V. Chokshi, Preksha Vinchhi, et al. · Turkish Journal of Pharmaceutical Sciences (2025) | TGRS Research Map | TGRS