U2AF65 mediated circPVT1 promotes NSCLC cell proliferation and inhibits ferroptosis through the miR-338-3p/GPX4 axis
U2AF65 stabilizes circPVT1 to promote NSCLC advancement through miR-338-3p suppression and GPX4 upregulation. Thus, circPVT1 and U2AF65 may be potential therapeutic targets in NSCLC.
Authors
- Jufen Wang
- Lujuan He (ORCID: https://orcid.org/0000-0003-2440-1792)
- Jiehan Jiang (ORCID: https://orcid.org/0000-0001-7516-8981)
- Shenggang Liu
- Zezhi Zhou
Institutions
- Central South University (CN)
- Changsha Medical University (CN)
- University of South China (CN)
Publication Details
- Journal
- Cell Biology and Toxicology
- Published
- 2025-05-14
- DOI
- https://doi.org/10.1007/s10565-025-10028-4
- Citations
- 2
- Primary Topic
- Circular RNAs in diseases
- Type
- article
- Field-Weighted Citation Impact
- 1.61
Funders
- Natural Science Foundation of Hunan Province