Evaluation of CRP SNV rs2808630 and acute proinflammatory biomarkers in patients with CKD and PLHIV with CKD: a case-control study
The presence of the CRP SNV does not appear to contribute to the development of CKD and has no association with inflammatory biomarkers. Though, genetically independent manner, hs-CRP levels are slightly different between groups and are underrated when related to the CKD stage in PLHIV. Also, high IL-6 concentrations are related to CKD progression, while IL-8 seems to have a better relation to CKD in PLHIV.
Authors
- Luz Alicia González-Hernández (ORCID: https://orcid.org/0000-0002-7163-0566)
- Jorge Fernando Topete-Reyes (ORCID: https://orcid.org/0000-0002-8465-9050)
- Zyanya Reyes-Castillo (ORCID: https://orcid.org/0000-0001-6696-0344)
- Andrea Torres-Rojas
- Adriana Valle-Rodríguez
- Pedro Martínez-Ayala (ORCID: https://orcid.org/0000-0002-0505-6340)
- Jaime Andrade‐Villanueva (ORCID: https://orcid.org/0000-0003-1948-655X)
- Jorge Hernández‐Bello (ORCID: https://orcid.org/0000-0001-8004-1811)
- Karina Sánchez-Reyes (ORCID: https://orcid.org/0000-0001-6839-0293)
- Jonathan Samuel Chavez-Iñiguez (ORCID: https://orcid.org/0000-0003-2786-6667)
- Monserrat Álvarez-Zavala (ORCID: https://orcid.org/0000-0003-0242-239X)
- Vida Verónica Ruíz-Herrera
Institutions
- Mexican Social Security Institute (MX)
- Universidad de Guadalajara (MX)
- Hospital Civil de Guadalajara (MX)
Publication Details
- Journal
- BMC Nephrology
- Published
- 2025-05-14
- DOI
- https://doi.org/10.1186/s12882-025-04138-8
- Primary Topic
- Inflammasome and immune disorders
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Universidad de Guadalajara