Cognitive impairment, mood, and fatigue in various multiple sclerosis subtypes: a one-year follow-up study
Cognitive impairments differed significantly across MS subtypes. While RRMS patients improved over one year and PPMS patients showed selective gains in one domain, SPMS showed no significant changes, indicating reduced cognitive reserve. These between-group differences suggest different cognitive trajectories. The findings underscore the need for tailored, holistic interventions for different MS subtypes.
Authors
- Hayrettin Tumani (ORCID: https://orcid.org/0000-0002-1647-6201)
- Herbert Schreiber (ORCID: https://orcid.org/0000-0002-4755-492X)
- Visal Tumani (ORCID: https://orcid.org/0000-0002-8569-6638)
- Ingo Uttner
- Daniela Taranu (ORCID: https://orcid.org/0000-0001-9165-4437)
- Jill Holbrook
- Luisa T. Balz (ORCID: https://orcid.org/0009-0002-8088-3386)
Institutions
- Universität Ulm (DE)
- University Hospital Ulm (DE)
- Neurological Surgery (US)
- Technische Hochschule Ulm (DE)
Publication Details
- Journal
- Journal of Neurology
- Published
- 2025-05-14
- DOI
- https://doi.org/10.1007/s00415-025-13115-y
- Citations
- 4
- Primary Topic
- Multiple Sclerosis Research Studies
- Type
- article
- Field-Weighted Citation Impact
- 5.89
Funders
- Universität Ulm