Single-cell transcription reveals hepatocyte-to-cholangiocyte reprogramming and biliary gene profile in biliary atresia
Dissecting the cellular source and function of cholangiocytes is essential to understand the pathological role of DR in BA. The identified specific biliary markers and TFs provide important insights into its potential diagnosis and mechanism exploration for BA in the future.
Authors
- Lingdu Meng (ORCID: https://orcid.org/0000-0002-0048-0687)
- Gong Chen (ORCID: https://orcid.org/0000-0003-3351-0819)
- Zhen Shen (ORCID: https://orcid.org/0000-0002-6287-6169)
- Fanyang Kong
- Junfeng Wang (ORCID: https://orcid.org/0000-0001-5477-1239)
- Shan Zheng (ORCID: https://orcid.org/0000-0002-9712-4573)
- Min Du (ORCID: https://orcid.org/0000-0001-7776-3987)
- Rui Dong (ORCID: https://orcid.org/0000-0001-9645-4768)
- Haodong Li (ORCID: https://orcid.org/0009-0000-5822-7353)
- Jiajian Yang (ORCID: https://orcid.org/0000-0001-9175-6572)
Institutions
- University of Electronic Science and Technology of China (CN)
- Chengdu Women's and Children's Central Hospital (CN)
- Children's Hospital of Fudan University (CN)
- Children’s Hospital of Fudan University Xiamen Branch (CN)
Publication Details
- Journal
- Hepatology Communications
- Published
- 2025-05-14
- DOI
- https://doi.org/10.1097/hc9.0000000000000710
- Citations
- 4
- Primary Topic
- Pediatric Hepatobiliary Diseases and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 8.03