Intestinal microbiota profiles of captive-bred cynomolgus macaques reveal influence of biogeography and age
We observed limited effects of age on the composition of the luminal microbiota in the profiled regions of the intestinal tract except when sex was included as a covariate. The enteric microbial communities of the small and the large intestine were, however, distinct, highlighting the limitations of frequently used faecal microbial profiling as a proxy for the intestinal microbiota. The identification of a number of putative novel microbial taxa contributes to knowledge of the full diversity of the cynomolgus macaque intestinal microbiome.
Authors
- Richard Evans (ORCID: https://orcid.org/0000-0002-1220-8605)
- David Baker (ORCID: https://orcid.org/0000-0002-8872-8711)
- Catherine Purse (ORCID: https://orcid.org/0000-0002-6024-1792)
- Simon G. P. Funnell (ORCID: https://orcid.org/0000-0002-4254-2751)
- Steve A. James (ORCID: https://orcid.org/0000-0003-2292-563X)
- Simon R. Carding (ORCID: https://orcid.org/0000-0002-2383-9701)
- Cynthia J. Moss
- Andrew R. Parker
- J. Scott Durham
Institutions
- Quadram Institute (GB)
- UK Health Security Agency (GB)
Publication Details
- Journal
- Animal Microbiome
- Published
- 2025-05-14
- DOI
- https://doi.org/10.1186/s42523-025-00409-9
- Citations
- 2
- Primary Topic
- Gut microbiota and health
- Type
- article
- Field-Weighted Citation Impact
- 1.61
Funders
- UK Research and Innovation
- Directorate for Biological Sciences
- Medical Research Council
- Biotechnology and Biological Sciences Research Council