HBV core protein enhances WDR46 stabilization to upregulate NUSAP1 and promote HCC progression

Our comprehensive data provides new insights into the mechanisms responsible for HBC-induced hepatocarcinogenesis. WDR46 and its downstream molecule, NUSAP1, may act as novel therapeutic targets for HBV-related tumors.

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Publication Details

Journal
Hepatology Communications
Published
2025-05-14
DOI
https://doi.org/10.1097/hc9.0000000000000680
Citations
2
Primary Topic
Hepatitis B Virus Studies
Type
article
Field-Weighted Citation Impact
2.71
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article

HBV core protein enhances WDR46 stabilization to upregulate NUSAP1 and promote HCC progression

Yujie Zhong, Xiucheng Pan, Renxian Tang, X. B. Liu et al.
2 citations
Hepatology Communications
Hepatitis B Virus Studies
2.71
article

HBV core protein enhances WDR46 stabilization to upregulate NUSAP1 and promote HCC progression

Yujie Zhong, Xiucheng Pan, Renxian Tang, X. B. Liu, Hongjuan You, Lu Yang, Kuiyang Zheng, Fanyun Kong, Xiangye Liu, Chen Li, Ruyu Liu, Rong Jiang, En-Si Bao, H X Zhang, Yuxin Wang
article en
2 citations

Abstract

Our comprehensive data provides new insights into the mechanisms responsible for HBC-induced hepatocarcinogenesis. WDR46 and its downstream molecule, NUSAP1, may act as novel therapeutic targets for HBV-related tumors.

Hepatology CommunicationsVol. 9(6)
Xuzhou Medical College (CN), Capital Medical University (CN), Beijing Ditan Hospital (CN)
Openalex Percentile: Top 10%
Hepatitis B Virus Studies
2.71
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