Spindle epithelial tumor with thymus-like elements (SETTLE): a surgical case diagnosed preoperatively using fine-needle aspiration cytology

A rare thyroid tumor, spindle epithelial tumor with thymic-like elements (SETTLE), was diagnosed preoperatively and treated surgically. SETTLE presents with characteristic histological features that must be recognized for accurate diagnosis. In addition, diagnosis through cytology is often challenging. The primary treatment for SETTLE is surgical intervention as radiotherapy and pharmacological treatments are generally not expected to be highly effective. Radical resection is the only effective treatment, making the selection of the surgical procedure according to the stage of the disease essential.

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Publication Details

Journal
Endocrinology Diabetes and Metabolism Case Reports
Published
2025-04-01
DOI
https://doi.org/10.1530/edm-25-0014
Primary Topic
Myasthenia Gravis and Thymoma
Type
article
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article

Spindle epithelial tumor with thymus-like elements (SETTLE): a surgical case diagnosed preoperatively using fine-needle aspiration cytology

Teru Chiyotanda, Keigo Shirahama, Yuichiro Z. Sato, Makoto Ikenoue et al.
Endocrinology Diabetes and Metabolism Case Reports
Myasthenia Gravis and Thymoma
article

Spindle epithelial tumor with thymus-like elements (SETTLE): a surgical case diagnosed preoperatively using fine-needle aspiration cytology

Teru Chiyotanda, Keigo Shirahama, Yuichiro Z. Sato, Makoto Ikenoue, Shinsuke Takeno, Satoru Meiri, Tsuyoshi Fukushima, Shun Munakata, Fumiaki Kawano, Kazuhiko Nakame, Atsushi Nanashima, Hideki Yamaguchi, Kazuhiro Higuchi
article en

Abstract

A rare thyroid tumor, spindle epithelial tumor with thymic-like elements (SETTLE), was diagnosed preoperatively and treated surgically. SETTLE presents with characteristic histological features that must be recognized for accurate diagnosis. In addition, diagnosis through cytology is often challenging. The primary treatment for SETTLE is surgical intervention as radiotherapy and pharmacological treatments are generally not expected to be highly effective. Radical resection is the only effective treatment, making the selection of the surgical procedure according to the stage of the disease essential.

Endocrinology Diabetes and Metabolism Case ReportsVol. 2025(2)
University of Miyazaki (JP)
Good health and well-being
Openalex Percentile: Top 83%
Myasthenia Gravis and Thymoma
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Spindle epithelial tumor with thymus-like elements (SETTLE): a surgical case diagnosed preoperatively using fine-needle aspiration cytology — Teru Chiyotanda, Keigo Shirahama, et al. · Endocrinology Diabetes and Metabolism Case Reports (2025) | TGRS Research Map | TGRS