A novel 16-hydroxy-palmitic acid tethered <scp>d</scp>-configured homo-chiral triphenylalanine based nanofibrillar scaffold with innate anticancer potential

A homochiral triphenylalanine system when tethered to 16-hydroxy-palmitic acid at the N-terminus displays excellent gelation propensity with mechanoresponsiveness and innate anticancer potential. We anticipate that the amphiphile-lactate derivative compound VI plays a pivotal role in addressing the cancer related challenges probably <i>via</i> an extrinsic apoptotic pathway.

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Publication Details

Journal
Chemical Communications
Published
2025-01-01
DOI
https://doi.org/10.1039/d5cc01500f
Citations
5
Primary Topic
Supramolecular Self-Assembly in Materials
Type
article
Field-Weighted Citation Impact
2.99

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article

A novel 16-hydroxy-palmitic acid tethered d-configured homo-chiral triphenylalanine based nanofibrillar scaffold with innate anticancer potential

Arindam Gupta, Rishabh Ahuja, Anita DuttKonar, Anindya Basu et al.
5 citations
Chemical Communications
Supramolecular Self-Assembly in Materials
2.99
article

A novel 16-hydroxy-palmitic acid tethered d-configured homo-chiral triphenylalanine based nanofibrillar scaffold with innate anticancer potential

Arindam Gupta, Rishabh Ahuja, Anita DuttKonar, Anindya Basu, Vaibhav Shivhare, Surendra Kumar Ahirwar, Dipesh Barde
article en
5 citations

Abstract

A homochiral triphenylalanine system when tethered to 16-hydroxy-palmitic acid at the N-terminus displays excellent gelation propensity with mechanoresponsiveness and innate anticancer potential. We anticipate that the amphiphile-lactate derivative compound VI plays a pivotal role in addressing the cancer related challenges probably <i>via</i> an extrinsic apoptotic pathway.

Chemical CommunicationsVol. 61(53)
Rajiv Gandhi Technical University (IN), University Grants Commission (IN), Indian Institute of Science Education and Research, Bhopal (IN)
Council of Scientific and Industrial Research, India, University Grants Commission, Science and Engineering Research Board
Openalex Percentile: Top 9%
Supramolecular Self-Assembly in Materials
2.99
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