Visible-Light-Driven Benzylic C–H Oxidation Catalyzed by Bisphosphonium Salt
An efficient photocatalytic method for the synthesis of carbonyl compounds through the oxidation of benzyl C-H bonds was developed. A series of acetophenone derivatives were successfully synthesized by utilizing a bisphosphonium salt catalyst and molecular oxygen as the oxidant. Preliminary mechanistic studies indicated that the reaction mechanism involved a free-radical pathway.
Authors
- Nan Jiang (ORCID: https://orcid.org/0000-0001-8394-3247)
- Qingmei Ge (ORCID: https://orcid.org/0000-0002-4918-4176)
- Wenfeng Zhao (ORCID: https://orcid.org/0009-0007-2093-6892)
- Hang Cong (ORCID: https://orcid.org/0000-0001-6855-5123)
- Aiqin Zhang (ORCID: https://orcid.org/0000-0003-0290-9800)
- Mao Liu (ORCID: https://orcid.org/0000-0002-2935-1117)
Institutions
- Guizhou University (CN)
Publication Details
- Journal
- The Journal of Organic Chemistry
- Published
- 2025-05-14
- DOI
- https://doi.org/10.1021/acs.joc.5c00495
- Citations
- 3
- Primary Topic
- Radical Photochemical Reactions
- Type
- article
- Field-Weighted Citation Impact
- 2.81
Funders
- National Natural Science Foundation of China
- Department of Education of Guizhou Province
- Natural Science Research Project of Guizhou Provincial Education Office