Orofacial manifestations associated with sickle cell anemia

Objective: Review the main orofacial manifestations commonly associated with Sickle Cell Anemia (SCA), emphasizing the clinical and radiographic characteristics of these changes, their pathophysiology, and their relationship with systemic complications. Bibliographic review: Sickle cell disease (SCD) is a term used to describe a group of hereditary hematological disorders characterized by sickling of the erythrocytes. Several factors associated with the disease increase susceptibility to changes in oral tissues. This study aimed to review the main orofacial manifestations commonly associated with Sickle Cell Anemia (SCA), emphasizing the clinical and radiographic characteristics of these changes, their pathophysiology, and their relationship with systemic complications. Final considerations: It is concluded that several factors associated with SCA can influence the development of some oral manifestations, directly impacting oral health and quality of life. Therefore, it is essential that the dentist knows these clinical, pathophysiological and radiographic characteristics for the correct management and approach of patients with sickle cell anemia.