A Two-Stage Phase 2, Multicenter, Randomized, Double-Blind, Placebo-Controlled Study to Evaluate the Safety and Efficacy of Ec-18 in Altering the Severity and Course of Oral Mucositis Secondary to Chemoradiation Therapy for Squamous Cell Cancers of t
EC-18 administered orally may be a safe and effective CRT-associated SOM intervention in patients with HNC.
Authors
- Stephen T. Sonis (ORCID: https://orcid.org/0000-0001-6480-2625)
- Arielle Lee
- Daniel Clayburgh (ORCID: https://orcid.org/0000-0002-3296-4926)
- Christina Henson (ORCID: https://orcid.org/0000-0002-5419-4125)
- Jeffrey Crawford (ORCID: https://orcid.org/0000-0002-1274-1354)
- Mahesh Kudrimoti (ORCID: https://orcid.org/0000-0001-7251-2687)
- Deborah J. L. Wong (ORCID: https://orcid.org/0000-0002-7811-7247)
- Krishna Rao (ORCID: https://orcid.org/0000-0002-1788-264X)
- Alessandro Villa (ORCID: https://orcid.org/0000-0002-1966-6000)
- Steve P. Lee (ORCID: https://orcid.org/0000-0001-7168-1542)
- Noah S. Kalman (ORCID: https://orcid.org/0000-0003-1299-3014)
- Ki Young Sohn
Institutions
- University of Kentucky HealthCare (US)
- Southern Illinois University School of Medicine (US)
- UCLA Health (US)
- Portland VA Medical Center (US)
- Tibor Rubin VA Medical Center (US)
- Miami Heart Research Institute (US)
- Oklahoma State University Oklahoma City (US)
- University of Oklahoma (US)
- The University of Texas Health Science Center at Tyler (US)
Publication Details
- Journal
- Cancers
- Published
- 2025-05-14
- DOI
- https://doi.org/10.3390/cancers17101663
- Citations
- 4
- Primary Topic
- Oral health in cancer treatment
- Type
- article
- Field-Weighted Citation Impact
- 6.07