Skin-Colored Papules on the Neck of a Postmenopausal Woman: A Diagnostic Challenge

A 64-year-old patient presented for management of symptomatic skin-colored papules symmetrically distributed over the lateral neck over the past two years, which failed to improve on multiple topical corticosteroids, antifungal creams, and topical calcineurin inhibitor. Histopathologic examination showed a regular epidermis with increased melanophages in the papillary dermis, without vacuolar degeneration of the basement membrane. Verhoeff Van Gieson stain highlighted a band-like zone of attenuated elastic fibers in the papillary dermis, while Von Kossa stain was negative for calcified fibers. PAS staining was negative for fungal organisms and Alcian blue showed no increase in dermal mucin.

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Publication Details

Journal
Dermatopathology
Published
2025-05-14
DOI
https://doi.org/10.3390/dermatopathology12020015
Primary Topic
Dermatological and Skeletal Disorders
Type
article
Field-Weighted Citation Impact
0.00
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article

Skin-Colored Papules on the Neck of a Postmenopausal Woman: A Diagnostic Challenge

Dorra Guermazi, Jason El Jalkh, Élie Saliba, Pia Maria Obeid et al.
Dermatopathology
Dermatological and Skeletal Disorders
article

Skin-Colored Papules on the Neck of a Postmenopausal Woman: A Diagnostic Challenge

Dorra Guermazi, Jason El Jalkh, Élie Saliba, Pia Maria Obeid, Aya Soubra
article en

Abstract

A 64-year-old patient presented for management of symptomatic skin-colored papules symmetrically distributed over the lateral neck over the past two years, which failed to improve on multiple topical corticosteroids, antifungal creams, and topical calcineurin inhibitor. Histopathologic examination showed a regular epidermis with increased melanophages in the papillary dermis, without vacuolar degeneration of the basement membrane. Verhoeff Van Gieson stain highlighted a band-like zone of attenuated elastic fibers in the papillary dermis, while Von Kossa stain was negative for calcified fibers. PAS staining was negative for fungal organisms and Alcian blue showed no increase in dermal mucin.

DermatopathologyVol. 12(2)
Brown University (US), Lebanese American University (LB)
Good health and well-being
Openalex Percentile: Top 88%
Dermatological and Skeletal Disorders
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