Fire needle pretreatment combined with ALA-PDT for Penile Bowen's disease: A case report
Bowen's disease (BD), squamous cell carcinoma (SCC) in situ, presents treatment challenges when located on the penis. Primarily concerning potential scarring and functional impairment following standard surgical excision (e.g., Mohs micrographic surgery). Aminolevulinic acid photodynamic therapy (ALA-PDT) may provide a valuable alternative, especially for this sensitive anatomical site. This report describes the successful treatment of a case of penile BD using fire needle pretreatment immediately preceding ALA-PDT. The patient achieved complete clinical and histological remission and remained disease-free at 2 years of follow-up.
Authors
- Tianming Ma (ORCID: https://orcid.org/0000-0001-5908-2846)
- Runqun Liu
- Xiaoqing Xiang (ORCID: https://orcid.org/0009-0003-6379-1962)
- Yunyun Cao
- Yanliang Li (ORCID: https://orcid.org/0009-0002-0560-5212)
Institutions
- Heilongjiang University of Chinese Medicine (CN)
- Longgang Central Hospital (CN)
- First Affiliated Hospital of Heilongjiang University of Chinese Medicine (CN)
- Heilongjiang Provincial Hospital (CN)
Publication Details
- Journal
- Photodiagnosis and Photodynamic Therapy
- Published
- 2025-05-14
- DOI
- https://doi.org/10.1016/j.pdpdt.2025.104631
- Primary Topic
- Dermatologic Treatments and Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00